Beckman Coulter Life Sciences Launches Biomek i3 Benchtop Liquid Handling System

Beckman Coulter Life Sciences has announced the Biomek i3 Benchtop Liquid Handler, expanding its long-standing Biomek automation platform into the low- to medium-throughput segment.

The Biomek i3 is positioned as a compact, cost-conscious automation system intended for research laboratories that require flexibility and reproducibility but lack the physical space, budget, or expertise typically associated with larger automation platforms.

Key specifications highlighted in the launch include:

  • Grid-based deck with 15 standard + 5 flex positions
  • 8-channel pipetting head with selective tip pickup
  • 1–1,000 µL volume range
  • Integrated gripper for ANSI/SLAS labware
  • On- and off-deck support for heating, cooling, shaking, tilting, and thermocycling
  • Touchscreen interface and drag-and-drop protocol design

The system targets genomic and drug discovery workflows, including sequencing, synthetic biology, epigenetics, cell-based assays, and ADME-Tox studies.

The benchtop liquid handling systems is becoming increasingly crowded with new announcements aiming to remove bottlenecks, ease of use, modularity, smaller footprints, and lower barriers to entry. Below is a table of the recent announcements:

Platform / Vendor Target Throughput Deck Capacity & Layout Pipetting Configuration Volume Range Tip Management Gripper & Labware Handling On/Off-Deck Device Support Software & UI Learning Curve Customization Flexibility Regulated / Semi-Regulated Suitability Typical User Profile
Beckman Coulter Life Sciences Biomek i3 Low–medium Grid-based deck with 15 standard + 5 flex positions Fixed 8-channel head with selective tip pickup 1–1,000 µL Selective tip pickup reduces waste Integrated gripper for ANSI/SLAS plates, lids, tip boxes Native support for heating, cooling, shaking, tilting, thermocycling Touchscreen with drag-and-drop workflow design Low Moderate (configuration-focused, not script-heavy) Strong alignment Small–mid biotech, assay development, labs new to automation
Opentrons OT-2 Low–medium Open deck, flexible labware placement Single or 8-channel modules (interchangeable) Broad, module-dependent Standard tip usage No native gripper (third-party solutions required) Limited native integration; extensible via custom hardware Python-based scripting (API-driven) Medium–High High (open-source hardware & software) Limited Academic labs, exploratory research, automation-savvy teams
Tecan Fluent Uno Medium Fluent-derived deck architecture Configurable pipetting arms Broad, application-dependent Advanced tip tracking and reuse options Integrated robotic handling Extensive ecosystem support Fluent software environment Medium High Strong Pharma, translational research, scale-up focused labs
Agilent Bravo Low–medium Compact, fixed deck layout Fixed multichannel head Optimized for genomics volumes Standard tip usage Limited robotic handling Strong plate handler and device compatibility Software-driven protocol configuration Medium Moderate Moderate–Strong Genomics cores, standardized assay labs
Hamilton Microlab STARlet Medium Highly configurable deck Multiple pipetting configurations available Broad, precision-focused Advanced tip handling options Integrated gripper and robotic transport Extensive peripheral and device support Venus software (logic-heavy configuration) High Very High Very Strong Precision-critical, customization-heavy environments

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