Beckman Coulter Life Sciences Launches Biomek i3 Benchtop Liquid Handling System

Beckman Coulter Life Sciences Launches Biomek i3 Benchtop Liquid Handling System

Beckman Coulter Life Sciences has announced the Biomek i3 Benchtop Liquid Handler, expanding its long-standing Biomek automation platform into the low- to medium-throughput segment.

The Biomek i3 is positioned as a compact, cost-conscious automation system intended for research laboratories that require flexibility and reproducibility but lack the physical space, budget, or expertise typically associated with larger automation platforms.

Key specifications highlighted in the launch include:

  • Grid-based deck with 15 standard + 5 flex positions
  • 8-channel pipetting head with selective tip pickup
  • 1–1,000 µL volume range
  • Integrated gripper for ANSI/SLAS labware
  • On- and off-deck support for heating, cooling, shaking, tilting, and thermocycling
  • Touchscreen interface and drag-and-drop protocol design

The system targets genomic and drug discovery workflows, including sequencing, synthetic biology, epigenetics, cell-based assays, and ADME-Tox studies.

The benchtop liquid handling systems is becoming increasingly crowded with new announcements aiming to remove bottlenecks, ease of use, modularity, smaller footprints, and lower barriers to entry. Below is a table of the recent announcements:

Platform / VendorTarget ThroughputDeck Capacity & LayoutPipetting ConfigurationVolume RangeTip ManagementGripper & Labware HandlingOn/Off-Deck Device SupportSoftware & UILearning CurveCustomization FlexibilityRegulated / Semi-Regulated SuitabilityTypical User Profile
Beckman Coulter Life Sciences Biomek i3Low–mediumGrid-based deck with 15 standard + 5 flex positionsFixed 8-channel head with selective tip pickup1–1,000 µLSelective tip pickup reduces wasteIntegrated gripper for ANSI/SLAS plates, lids, tip boxesNative support for heating, cooling, shaking, tilting, thermocyclingTouchscreen with drag-and-drop workflow designLowModerate (configuration-focused, not script-heavy)Strong alignmentSmall–mid biotech, assay development, labs new to automation
Opentrons OT-2Low–mediumOpen deck, flexible labware placementSingle or 8-channel modules (interchangeable)Broad, module-dependentStandard tip usageNo native gripper (third-party solutions required)Limited native integration; extensible via custom hardwarePython-based scripting (API-driven)Medium–HighHigh (open-source hardware & software)LimitedAcademic labs, exploratory research, automation-savvy teams
Tecan Fluent UnoMediumFluent-derived deck architectureConfigurable pipetting armsBroad, application-dependentAdvanced tip tracking and reuse optionsIntegrated robotic handlingExtensive ecosystem supportFluent software environmentMediumHighStrongPharma, translational research, scale-up focused labs
Agilent BravoLow–mediumCompact, fixed deck layoutFixed multichannel headOptimized for genomics volumesStandard tip usageLimited robotic handlingStrong plate handler and device compatibilitySoftware-driven protocol configurationMediumModerateModerate–StrongGenomics cores, standardized assay labs
Hamilton Microlab STARletMediumHighly configurable deckMultiple pipetting configurations availableBroad, precision-focusedAdvanced tip handling optionsIntegrated gripper and robotic transportExtensive peripheral and device supportVenus software (logic-heavy configuration)HighVery HighVery StrongPrecision-critical, customization-heavy environments

Labcritics Alerts / Sign-up to get alerts on discounts, new products, apps, protocols and breakthroughs in tools that help researchers succeed.

Science communicator with more than two decades of experience covering traditional and modern lab technologies such as NGS, LIMS and more recently AIxBio and Decentralized Science. Personally involved in building Unblock Research a platform of concentrated efforts to remove research bottlenecks.