Genome Editing

CRISPR and the wider editing toolkit – delivery, specificity, and the systems engineered to make edits safer and more precise.

46 articles

crispr-cas9

A Novel Cas9 Recognizes More DNA Targets

Researchers from the Massachussets General Hospital (MGH) have engineered the Cas9 nuclease from Staphylococcus aureus (SaCas9) to recognize more targets. The prokaryote RNA-guided immune system, used as a genome...

Basic Research

IDT Launches New CRISPR with Increased Editing Efficiency

Integrated DNA Technologies (IDT) has launched the  Alt-R™ CRISPR-Cas9 System, a genome editing tool based on the S. pyogenes CRISPR/Cas immune system. IDT has optimized CRISPR...

Basic Research

CRISPR-Edited Mini-Kidneys as Disease Models

Researchers from the University of Washington have obtained mini-kidneys from CRISPR-edited human pluripotent stem cells, modified to mimick genetic diseases. The organoids work as disease...

Biomedicine

CRISPR/Cas9 Eliminates Viral Transmission Risk in Xenotransplants

Researchers from  Harvard Medical School in Boston have successfully deactivated 62 viruses in embryo pigs. The achievement was possible thanks to the CRISPR/Cas9 genome editing technology. The...

Bioengineering
Nanopore proteins

Nanopores Found Useful in Detecting Single Molecule Movements

Nanopore’s are proving to be useful for more than just DNA sequencing. The pico sized wonder’s have shown that they can even identify single molecular...

Biotechnology
CPF1 mediated gene editing in humans

CRISPR/CPF1: New Simpler CRISPR Protein May Cut Patent Fights Short

New CRISPR discovered by original CRISPR/Cas9 discovery team promises simpler and more flexible gene editing with fewer legal tangles. Broad Institute Researchers at Massachusetts Institute...

Bioengineering
Next Gen Seqencing Helix

The Rise of CRISPR Based Startups

CRISPR/Cas9 gene editing technology seems to be the only thing that everyone is talking about nowadays and maybe the only thing researchers want to work...

Bioengineering

A Single Cas Protein for Gene Edition and Regulation

CRISPR-Cas9 is know for its ability to edit eukaryotic genomes, but from now it could be famous for its multifunctionality. MIT and Harvard laboratories have led a...

Basic Research