Techniques

Methods and protocols in practice – how researchers actually run experiments, and the techniques shifting what is possible at the bench.

218 articles

xenopat

Xenopat: Your Tumor in a Mouse

Labcritics visited Xenopat, an innovative company dedicated to the orthotopic implantation of human tumors in mice. This technology allows Xenopat to offer services to companies...

Biomedicine
iproteos

Teresa Tarragó: “Crowdfunding is a Source of Financing for Early Stage Biotechs”

Labcritics was at Iproteos’ facilities talking to Teresa Tarragó, CEO and co-founder of this innovative company. Iproteos combines computational chemistry with modern synthesis methods to generate...

Biomedicine
crispr-cas9

CRISPR as a Recorder of Molecular Activity

Researchers from Harvard University have succesfully proved that CRISPR can work as a recorder of molecular events. Synthetic DNA molecules introduced in bacteria over a...

Basic Research
crispr-cas9

CRISPR/Cpf1 Edits Mice Embryos Without Off-Target Effects

Researchers at the IBS Center for Genome Editing in South Korea have successfully created mutant mice using CRISPR/Cpf1. The alternative to the well-known CRISPR/Cas9 system can...

Bioengineering

Ultrashort Laser Pulses Reduce Off-Target Effects of Radiotherapy

Researchers from the Tata Institute of Fundamental Research in India have developed an innovative technique to cause DNA damage in a controlled manner. Short, intense pulses...

Cancer Research

Size Exclusion Chromatography Tips and Tricks

Size exclusion chromatography (SEC) is a technique that allows to perform molecular separation by size. Some common SEC applications are protein purification, protein-protein interaction assays,...

Blog

Quantification of Genome Editing Events Using ddPCR

Bio-Rad presented at Analytica the ultra-sensitive properties of digital droplet PCR (ddPCR) to quantify homology directed repair (HDR) and non-homologous end joining (NHEJ) events in...

Biomedicine

Droplet Digital PCR to Measure Tumor Load

Christof Winter from Technische Universität München presented at Analytica the innovative use of droplet digital PCR to measure tumor load by non-invasive means. The technique...

Cancer Research