Tools of the Trade

A curated directory of the software researchers actually use - from literature discovery and reference managers to electronic lab notebooks, analysis pipelines, imaging and the new generation of AI research tools. Every entry is written by hand, and every outbound link is checked.

  • 254 tools listed
  • 20 categories
  • 214 free or open source
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94 tools in Analysis

SAMtools

Sequence Alignment Data Toolkit

AnalysisBioinformaticsFREE, OPEN SOURCE

Scanpy

Python Toolkit for Single-Cell Analysis

AnalysisBioinformaticsFREE, OPEN SOURCE

scvi-tools

Probabilistic Models for Single-Cell Omics

AnalysisBioinformaticsFREE, OPEN SOURCE

Seurat

R Toolkit for Single-Cell Genomics

AnalysisBioinformaticsFREE, OPEN SOURCE

Snakemake

Python Workflow Management System

AnalysisBioinformaticsFREE, OPEN SOURCE

VMD

Molecular modelling and visualization software

Zenodo

Open Repository for Data, Software and Publications

Built something researchers should know about?

We add tools on reader suggestions, and we list open-source projects and one-person side projects on the same terms as funded platforms. Listing is free, there is no paid placement, and we write the entry ourselves after trying the tool.

Missing a tool?

Tell us what your lab runs on. Listing is free and we do not take payment for placement.

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How entries are chosen

  • It has to be alive. Links are verified, and tools that die or get acquired into irrelevance are retired rather than left to rot.
  • Researchers have to actually use it. Adoption in real labs matters more than a polished launch page.
  • Cost is stated plainly. Free, open source, freemium or paid - including when "free for academics" comes with conditions.
  • No paid placement. Nobody buys their way onto this list, and there are no affiliate links.
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What is in here

The directory covers the whole research workflow: planning and funding, literature discovery, reference management, lab notebooks and inventory, analysis and computation, figures and visualisation, writing, publishing, and data sharing. Alongside the long-established tools you would expect, it tracks the AI workbenches and foundation models now reshaping how computational research gets done.