Genome Editing

CRISPR and the wider editing toolkit – delivery, specificity, and the systems engineered to make edits safer and more precise.

46 articles

phage

Anti-CRISPR Proteins from Prophages Discovered in Proteobacterial Genomes

Researchers from the University of Toronto and the University of Otago have discovered five new proteins that block the bacterial CRISPR/Cas immune system. The anti-CRISPR proteins are...

Basic Research
crispr-cas9

CRISPR/Cpf1 Edits Mice Embryos Without Off-Target Effects

Researchers at the IBS Center for Genome Editing in South Korea have successfully created mutant mice using CRISPR/Cpf1. The alternative to the well-known CRISPR/Cas9 system can...

Bioengineering

Quantification of Genome Editing Events Using ddPCR

Bio-Rad presented at Analytica the ultra-sensitive properties of digital droplet PCR (ddPCR) to quantify homology directed repair (HDR) and non-homologous end joining (NHEJ) events in...

Biomedicine
crispr-cas9

New CRISPR Nuclease Cuts Both DNA and RNA

CRISPR/Cas9 co-discoverer Emmanuelle Charpentier and collaborators from Germany and Sweden have found that Cas nuclease Cpf1 cleaves DNA and RNA. Cpf1 cuts a precursor of crRNA to produce the...

Bioengineering
Veritas Genomics

It’s Here!! $1,000 Whole Genome Sequencing, With Results Browsable on Smartphones

Veritas Genetics has announced its $1,000 whole genome sequencing service whose results will be browsable on smartphones. The MyGenome service announced last year and set to...

Bioinformatics
crispr-cas9

Human Embryo Gene Editing Authorized for Research Purposes

The Human Fertilisation and Embryology Authority (HFEA) has approved the use of the gene editing tool CRISPR on human embryos for research purposes. After a...

Bioengineering
Cas9

CRISPR/Cas9 Editing Efficiency Increased by 60%

Researchers from UC Berkeley have improved CRISPR/Cas9 gene editing performance by 60%. The team designed a specific DNA template that has the desired sequence and...

Bioengineering
takaraclontech logo

Clontech Gesicles Improve CRISPR/Cas9 Performance

Clontech has launched the Guide-it CRISPR/Cas9 Gesicle Production System, a new technology that improves CRISPR/Cas9 delivery and reduces its footprint. Cas9 endonucleases and target-specific sgRNAs are encapsulated...

Bioengineering