Basic Research

Fundamental science without an immediate application – the mechanisms, structures and phenomena later work is built on.

78 articles

Protein 3D Structure Reveals New Information About Neurotransmitters Release

Scientists from the SLAC National Accelerator Laboratory, Stanford University and Stanford School of Medicine have solved the 3D structure of the SNARE-synaptotagmin-1 complex that controls...

Basic Research

Ribosomes can translate the untranslated region

Scientists from the Johns Hopkins University School of Medicine have discovered that ribosomes can translate mRNA in the Three prime untranslated region (3’UTR). Depletion of...

Basic Research

Fruit-Fly Nervous System Imaged at Nearly Single-Cell Resolution

  Researchers from the Howard Hughes Medical Institute in Virginia have recorded the whole neural activity of a fruit fly for the first time. The team...

Basic Research

Genomic Imprinting Can Target Just a Few Cells

Scientists from the University of Utah School of Medicine have discovered that genomic imprinting can be targeted to subregions of tissues or small clusters of...

Basic Research

First Epigenetic Mechanism Involving Histone Tails Solved at Atomic Level

Researchers from the Institute for Research in Biomedicine (IRB Barcelona), the University of Cambridge, and New York University have discovered the structural mechanism of chromatin...

Basic Research

Ribo-T : Ribosome with Linked Subunits Reads Desired RNA

Scientists from the University of Illinois at Chicago and Northwestern University have engineered the Ribo-T, a tethered ribosome that could be used to produce drugs and new...

Basic Research

Repetitive Nucleotide Sequences Affect Translation Independently of the Encoded Amino Acids

Nucleotides can affect ribosomal translation. A study by scientists from Johns Hopkins University School of Medicine has discovered that ribosome stalling can come from the...

Basic Research

Fractal Globule Model of Chromatin Packing Reinforced

Scientists from Lomonosov Moscow State University have strengthened the fractal globule model of chromatin packing. In their Physical Review Letters paper, the researchers present a...

Basic Research